The Dominion Theatre is a West End theatre and former cinema on Tottenham Court Road. The Dominion was home to the long-running musical We Will Rock You played at the theatre from 14 May 2002 until 31 May 2014. It was also home to the London auditions of Britain's Got Talent and from February to April 2016 to War of the Worlds.

Over several years, the theatre has undergone a rolling programme of refurbishment which has included reclaiming the area above the main foyer as a studio for rehearsals or events (2008), and reclaiming the offices in Nederlander House, which were originally part of the theatre but had been rented as commercial office space. Within this area, originally listed on the theatre plans as a 'Boardroom', a new Boardroom space has been created (2011). Following the closure of We Will Rock You, the theatre remained dark for 15 weeks, during which time owners undertook a mass programme of refurbishment, including replacing carpets, painting and restoring architectural features, refurbishing seats, renovating the 'front of house' toilets and bars, and updating much of the backstage facilities, including the flying system. This £6 million restoration programme was completed in 2017 with the unveiling of a brand new double-sided LED screen, the largest and highest resolution projecting screen on the exterior of a West End theatre.

Since re-opening on 16 September 2014, the Dominion Theatre has been home to a number of short run musicals and spectaculars, including Evita (September 2014), White Christmas (November 2014), Lord of the Dance (March 2015) and the London premiere of Elf (October 2015). Between March 2017 – January 2018, the Dominion Theatre was home to An American in Paris.

In addition to hosting musicals in recent years, the theatre has also hosted a number of regular charity events, including MADTrust's West End Eurovision (2012, 2013, 2014) and West End Heroes (2013, 2014, 2015). 'West End Heroes' was produced by the theatre and brought together stars from current West End Shows, with musicians, from all the armed forces. The second event, in 2014, was hosted by Michael Ball.

The Dominion is also currently home to Hillsong Church every Sunday.